Nytol®
Have you ever felt tired but no matter what you try, you simply can't sleep at night? Around 1 in 3 people will struggle to get a good night’s sleep but it doesn’t have to be that way.¹ At Nytol®, each evening we join in your effort to combat sleepless nights.
Medicated sleep aids
Medicated sleep aids for the temporary relief of sleep disturbances.
Herbal sleep aids
Herbal remedies with natural active ingredients used to aid restful sleep.
Liquid sleep aids
Easy to swallow alternatives to non-prescription sleeping tablets.
Browse the Nytol® range
Helping you sleep better
On average, 1 in 3 people will experience some form of insomnia or ongoing sleeplessness in their lifetime³. The long nights, tossing and turning...can affect productivity at work, the ability to cope with stress, mental health and physical health as a result⁴.
If sleep deprivation is affecting you, we’re here to help get you back on track. Using sleep aids might be a helpful way to get the sleep you need, however, there might be some other contributing factors that could be keeping you up at night. Here, we offer some advice and tips to help you address some of the possible factors.

Are you experiencing a chronic sleep condition?
Sometimes, taking some time to understand why you’re not getting enough sleep at night can be the first step to resolving the issue. Firstly, it’s important to identify whether you’re experiencing a chronic sleep condition or whether this is a temporary spell of sleeplessness.
If you think you’re experiencing a chronic sleep condition like insomnia or sleep apnoea, it’s important to speak to your GP.

Removing poor sleep habits
There are plenty of distractions and disturbances that affect our ability to sleep. The solution to your sleeplessness could be as simple as making small improvements to your sleep habits and using a sleep aid to give your body clock a little nudge in the right direction. Here are some everyday activities which could be affecting the amount of sleep you get when done too close to bedtime⁵:
• Using electronic devices like your phone, games console, TV.
• Exposure to bright lights.
• Exercise/rigorous exercise.
• Eating a large meal.
• Worrying or replaying events from the day.
• Working in bed.

Tips to help you sleep better
There are lifestyle and environmental changes which you can make to help you improve your quality of sleep. These aren’t quick wins and often the tips below will need to be combined together to help you make sleep a priority. However, if you’re struggling to nod off at night, here are some ideas that might be able to help:
• Go to sleep and wake up at regular times³
• Keep to a regular bedtime routine³
• Ensure your sleep environment is as restful and calming as possible
• Put your tech away at least an hour before bed
• Keep your bed just for sleeping (avoid working or watching TV in bed)
• Try reading before going to sleep
• Try to cut back on your caffeine and alcohol intake⁶
• Record your progress in a sleep diary⁷
• Practice meditation and mindfulness⁸

Give your body clock a helping hand
If you’re experiencing sleeplessness, it can be helpful to give your body clock a little nudge back into a routine with the help of Nytol®. Nytol® sleep aids are made to help you get a good night’s sleep.

Nytol® frequently asked questions
What does Nytol® contain and how does it work?
expand_moreNytol provides a variety of sleep aids to suit your needs, all of which are used to help you get a good night’s sleep:
Nytol Original and Nytol One-A-Night both contain diphenhydramine hydrochloride, a commonly used antihistamine. It works by blocking the normal actions of histamine, the chemical that stimulates arousal-promoting areas of the brain. This helps you to drift off into a restful, deeper sleep and works by reducing alertness and promotes that first drowsy stage of sleep.
Nytol Herbal tablets are a traditional herbal sleeping aid and contains a blend of herbal ingredients including hops, valerian and passion flower. These ingredients have traditionally been used as sleeping aids for a peaceful night’s sleep.
Nytol Herbal Simply Sleep One-A-Night contains a natural active ingredients called Valerian root extract which has been used for decades to induce sleep and promote calmness.
Is Nytol® safe to use?
expand_moreWhilst all medicines can have side effects, they’re approved on the basis of their quality, safety and efficacy. The active ingredients used in Nytol are no different and have been used for many decades. Nytol should be used in line with the instructions on pack.
Will I feel groggy the next day after taking Nytol®?
expand_moreA morning after effect is unlikely with a full night’s sleep (around 8 hours) and you should wake-up feeling refreshed. When using Nytol its important to make sure you follow the instructions on the pack and in the leaflet.
Will I get dependent on taking Nytol®?
expand_moreOver-the-counter sleep medicines such as Nytol (Diphenhydramine) are used for treating occasional sleeplessness and are unlikely to cause dependency if used according to the instructions. If symptoms persist for longer than two weeks, consult a pharmacist or GP.
How fast does Nytol® work?
expand_moreNytol Original and Nytol One-A-Night should be taken at least 20 minutes before going to bed.
Nytol Herbal products should be taken 30 minutes to 1 hour before going to bed. Nytol Herbal products should be taken continuously for 2 to 4 weeks.
Can I take Nytol® if I wake up in the middle of the night?
expand_moreIt’s best to take Nytol before going to bed in line with the instructions on the pack and in the leaflet. However, Nytol can be taken during the night if you still have time to get a full night’s sleep (around 7 to 8 hours).
Can I use more than one of the Nytol® sleep aid products at once?
expand_moreIt is not recommended to take more than one product in the Nytol range at the same time. We suggest using the Nytol products as directed following the instructions on the pack and in the leaflet.
References
¹Insomnia- NHS
²Based on sales data - to verify contact: verify@perrigo.com
³Insomnia- NHS
⁴The effects of sleep deprivation – Johns Hopkins Medicine
⁵Sleep Hygiene Tips - Headspace
⁶Sleep hygiene: An information guide – NHS
⁷How to get to sleep – NHS
⁸Meditation for sleep - Headspace
Nytol Liquid caramel flavour oral solution, Nytol One-A-Night and Nytol Original 25mg Tablets contain diphenhydramine. Aids to the relief of temporary sleep disturbances for adults. Nytol Herbal Tablets. Nytol Herbal Simply Sleep One-A-Night tablets contain Valerian root extract. Traditional herbal medicinal products for use in the temporary relief of sleep disturbances exclusively based on long-standing use as traditional remedies. Nytol Herbal Simply Sleep & Calm Elixir contains Valerian root extract. A traditional herbal medicinal product for use in temporary relief of symptoms of mild anxiety and to aid sleep, exclusively based on long-standing use as a traditional remedy. Always read the leaflet.
UK/2021-0597